Flexeril Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

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Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor can diabetics take flexeril may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine’s side effects. Take this medication by mouth with or without food as directed by your doctor.

Flexeril disease interactions

You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. You can call (or for the deaf and the hard of hearing) to talk to a pharmacist about your medication questions. Our pharmacists are available by phone every night from 5pm to 9am – when your community pharmacist may be unavailable. There are many ways you can add physical activity to your healthy lifestyle, no matter your age or activity level.

The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment). The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine plasma concentrations. Despite package insert warnings, tizanidine and CYP1A2 inhibitors are commonly co-prescribed. Ask your pharmacist any questions you have about refilling your prescription. AddictionResource aims to present the most accurate, trustworthy, and up-to-date medical content to our readers.

Cyclobenzaprine (Flexeril) Uses, Side Effects, & Risks

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.

• Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose.
• In order to protect against the rare but potentially critical manifestations described above, obtain an ECG and immediately initiate cardiac monitoring.
• To submit your question about physical activity, please complete the form below.
• This document does not contain all possible drug interactions.

St. John’s wort, a plant-based supplement used to treat depression, as well as ginseng, ginko biloba and milk thistle, should not be used with many chemotherapy drugs, according to Dr. Kellman. Because licorice extract and grapefruit juice are also metabolized in the liver, Dr. Kellman says patients on certain chemotherapy drugs shouldn’t take them. The findings, reported in the March issue of Clinical Pharmacology & Therapeutics, demonstrate an interaction between tizanidine and strong CYP1A2 inhibitors in routine clinical practice. Clinicians should avoid co-prescribing these medications, particularly in patients at higher risk of severe hypotension, the authors conclude. Those using both may need to reduce either their cannabis or their cyclobenzaprine use, and speaking to a doctor about this is the best option. Cyclobenzaprine belongs to a class of drugs called muscle relaxants.

Do not use it later for another condition unless your doctor directs you to do so. During pregnancy, this medication should be used only when clearly needed. In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward. Acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. Safety and effectiveness of FLEXERIL in pediatric patients below 15 years of age have not been established. It is not known whether this drug is excreted in human milk.

Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center. They found that severe hypotension occurred more often in the tizanidine group than the cyclobenzaprine group. The risk of severe hypotension was higher in patients with more comorbidities and those who used three or more antihypertensive drugs.

Mixing alcohol with Flexeril may worsen its side effects and cause new symptoms to arise, so taking the two together is not recommended and must be resisted. Flexeril and alcohol are both central nervous system (CNS) depressants, with each of them having its own effective means of relaxing or easing the pain. However, mixing them and using them together would be unwise and may lead to dangerous and devastating effects. Cyclobenzaprine warnings, comprising the effects of using each of these medications on their own include a slowing of the mental faculties, drowsiness, lightheadedness, and lowered motor coordination. When used together, these effects may be exacerbated, increasing the risk of an accident.

Our writers and reviewers are experienced professionals in medicine, addiction treatment, and healthcare. AddictionResource fact-checks all the information before publishing and uses only credible and trusted sources when citing any medical data. The Verified badge on our articles is a trusted sign of the most comprehensive scientifically-based medical content. If you have any concern that our content is inaccurate or it should be updated, please let our team know at [email protected]. When it comes to the matter of drug interactions between Cyclobenzaprine and other drugs, there is a lot to look out for and factors to be considered. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.